Geriatric Neuroscience Research
>5 Episodes Every Single Week. Bringing you the latest research in geriatric neuroscience.
Episodes
16 episodes
Detection of Alzheimer’s disease with smiles and conversations with a chatbot [A.I.]
STUDY:Takeshige-Amano, H., Oyama, G., Ogawa, M. et al. Digital detection of Alzheimer’s disease using smiles and conversations with a chatbot. Sci Rep 14, 26309 (2024). https://doi.org/10.1038/s41598-024-77220-0
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13:20
Biases in genome-wide association studies based on parental history of AD [A.I.]
STUDY:Wu, Y., Sun, Z., Zheng, Q. et al. Pervasive biases in proxy genome-wide association studies based on parental history of Alzheimer’s disease. Nat Genet (2024). https://doi.org/10.1038/s41588-024-01963-9
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13:24
Dementia Presence and Severity Detection in Electronic Health Records [A.I.]
STUDY:Vyas A, Aisopos F, Vidal ME, Garrard P, Paliouras G. Identifying the presence and severity of dementia by applying interpretable machine learning techniques on structured clinical records. BMC medical informatics and decision making. ...
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12:59
BPS and Brain Volumes in Community-Dwelling Older Adults
STUDY:Tachibana, A., Iga, Ji., Ozaki, T. et al. Behavioral and psychological symptoms and brain volumes in community-dwelling older persons from the Nakayama Study. Sci Rep 14, 26097 (2024). https://doi.org/10.1038/...
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8:50
The HOME Study: PICLP and Time Spent in Hospital [A.I.]
This research paper describes a multicenter randomized controlled trial called The HOME Study, which investigated the effectiveness and cost-effectiveness of a novel approach to psychiatric care called Proactive Integrated Consultation-Liaison ...
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20:14
White Matter and Cognitive Decline in Major Depressive Disorder [A.I.]
This research investigates the relationship between changes in white matter microstructure and cognitive decline in individuals with major depressive disorder (MDD). The study follows a large cohort of participants with MDD and healthy controls...
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11:23
Amyloid Beta and Ferroptosis Pathway Link in AD progression [A.I.]
This research article investigates the link between amyloid beta (Aβ), a hallmark protein associated with Alzheimer's disease (AD), and ferroptosis, a type of programmed cell death. The researchers analyzed post-mortem brai...
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13:08
Dementia: Cognitive Stimulation Therapy, Reminiscence Therapy, Behavioural Therapies
Studies:Spector A, Thorgrimsen L, Woods BO, Royan L, Davies S, Butterworth M, Orrell M. Efficacy of an evidence-based cognitive stimulation therapy programme for people with dementia: randomised controlled trial. The British Journal of Psyc...
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16:12
P-Tau in CSF Extracellular Vesicles in Alzheimer’s disease [A.I.]
STUDY:Sattarov, R., Havers, M., Orbjörn, C. et al. Phosphorylated tau in cerebrospinal fluid-derived extracellular vesicles in Alzheimer’s disease: a pilot study. Sci Rep 14, 25419 (2024). https://doi.org/10.1038/s41598-02...
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15:40
Management of Dementia Symptoms (BPSD): Clinical Guidelines
Timeline0:00:00 Intro0:00:34 BPSD Guidelines Intro0:01:28 Agitation management: Non-pharmacologic & Pharmacologic0:03:27 Psychosis management: Non-pharmacologic & Pharmacologic<...
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7:47
APOE Genotypes and Dementia Risk: Mechanisms and Clinical Implications
STUDIES:Laws SM, Hone E, Gandy S, Martins RN. Expanding the association between the APOE gene and the risk of Alzheimer's disease: possible roles for APOE promoter polymorphisms and alterations in APOE transcription. Journal of neuroche...
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13:04
Remote Home-Based Brain Stimulation: A Breakthrough Treatment for Depression in Older Adults
STUDY:Woodham, R.D., Selvaraj, S., Lajmi, N. et al. Home-based transcranial direct current stimulation treatment for major depressive disorder: a fully remote phase 2 randomized sham-controlled trial. Nat Med (2024). https...
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14:27
Types of Dementia and Current Pharmacological Treatments for Dementia
STUDIES:Rizzi L, Rosset I, Roriz-Cruz M. Global epidemiology of dementia: Alzheimer’s and vascular types. BioMed research international. 2014;2014(1):908915.Smits LL, van Harten AC, Pijnenburg YA, Koedam EL, Bouwman FH, Sisterma...
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23:10
Amyloid Beta and Tau Association in Asymptomatic Older Adults [A.I.]
STUDY:Gallego-Rudolf J, Wiesman AI, Pichet Binette A, Villeneuve S, Baillet S, PREVENT-AD Research Group. Synergistic association of Aβ and tau pathology with cortical neurophysiology and cognitive decline in asymptomatic older adults. ...
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7:36
Eligibility for Disease Modifying Therapies (DMTs) in Dementia [A.I.]
STUDIES:Dobson R, Patterson K, Malik R, Mandal U, Asif H, Humphreys R, Payne M, Eng O, Huzzey L, Clare A, Green K. Eligibility for antiamyloid treatment: preparing for disease-modifying therapies for Alzheimer’s disease. Journal of Neur...
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14:08